l carnitine for valproic acid overdose Intoxication Role of L-carnitine in Cardiovascular

2.2.1 Oxidative stress and mitochondrial dysfunction METH significantly increases the production of ROS and reactive nitrogen species, overwhelming antioxidant defenses in neurons

Carnitine also serves a critical buffering function by accepting excess acyl groups that accumulate during periods of high metabolic flux (intense exercise, fasting)

Bu tama mekanizmas, ya yakm srecinin desteklenmesine ve enerji metabolizmasnn daha dzenli almasna katk sunar

Oral L-carnitine supplementation and exercise performance

Based on the evidence that heat-shock proteins (Hsps) can exert neuroprotective effects against oxidative stress-related injury and that nutritional antioxidants are able to upregulate Hsps in neurons, use of nutritional antioxidants such as carnitine/acetyl-L-carnitine has been advocated to counteract the oxidative stress-induced brain damage in Alzheimer's disease [67, 119]